Abstract
ABSTRACT: BACKGROUND : Gastric cancer is the the fourth most common cancer and the second leading cause of cancer-related deaths. Gastric cancer is a major cause of cancer morbidity and mortality worldwide. OBJECTIVE: To estimate the immunohistochemical expression of epidermal growth factor receptor(EGFR) in the gastric cancer in relation to other parameters like grade and stage. METHODS: Formaline fixed ,paraffin-embedded blocks from 51 patients (29 male and 22 female) with gastric carcinoma were included in this study. Ten biopsies of normal gastric tissue were selected as a control group. Envision (DAKO) technique was applied to study the immunohistochem- ical expression of EGFR in paraffin embedded sections of gastric cancer. RESULTS: Positive immunohistochemical expression of EGFR was seen in 41.2% of cases as both membranous and cytoplasmic brown staining while there was negative staining in the normal control group (p
Recommended Citation
F.Hashim, Ali; R.Al-Obaidie, Salim; and F.Hassan, Farah
(2016)
"Epidermal Growth Factor Receptor (egfr) Immunohistochemical Expression in Gastric Carcinoma,"
Iraqi Postgraduate Medical Journal: Vol. 15:
Iss.
3, Article 40.
Available at:
https://www.ipmj.org/journal/vol15/iss3/40