CD71Expression Pattern in Lymphocytes Among Rheumatoid Arthritis Patients
Abstract
ABSTRACT: BACKGROUND: Abnormal lymphocyte activation status have been described in rheumatoid arthritis. Suggesting an increased need for iron as a source of energy. OBJECTIVE: To evaluate the cellularexpression pattern ofTransferrin receptor(CD71)proteinin the peripheral blood lymphocytes, PATIENTS &METHODS: This study involved forty-six rheumatoid arthritis patients 42 female and 4 male, age ranged from 25-66 years collected from AL-Kadhemia teaching hospital were examined and compared with 17 healthy control individuals of similar ages. Lymphocytes were separated from peripheral blood samples,the assessment of their cellular expression of cluster of differentiation 3 and CD71by immunofluorescent staining method. RESULTS: The results showed abundant accumulation of CD3 T lymphocytes in the peripheral circulation of rheumatoid arthritispatients in comparison with controls with increased transferrin receptor expression in rheumatoid arthritisgroup (p
Recommended Citation
Ghazi, Haider Faisal; Al-Obaidi, Asmaa Baqir; and Alalsaidissa, Jaffar Nouri Jaffar
(2016)
"CD71Expression Pattern in Lymphocytes Among Rheumatoid Arthritis Patients,"
Iraqi Postgraduate Medical Journal: Vol. 15:
Iss.
4, Article 10.
Available at:
https://www.ipmj.org/journal/vol15/iss4/10