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Abstract

BACKGROUND: Spasticity is a motor disorder characterized by a velocity-dependent increase in muscle tone with exaggerated tendon jerks, resulting from hyperexcitability of the stretch reflex, as a component of the upper motor neuron syndrome. OBJECTIVE: To evaluate the effect of intrathecal baclofen therapy after one to five years of treatment. PATIENTS AND METHODS: Aretrospective questionnaire-based study was done including 20 patients operated for intrathecal baclofen pump insertion at neurosciences hospital from 1/1/2013 to 1/1/2018, RESULTS: According to GMFCS in C.P, only those who were grade 4 or 3 had benefit, while grade 5 patients only improved easier diapering and transfer. From 8 spinal cord injury cases, 7 had improvement, while both M.S. cases were improved, but one of them started to have tolerance four years after implantation.  Eighteen out of 20 patients were satisfied from ITB therapy One patient suffered from side effects (nausea, drowsiness) only after the test dose, and no side effects were mentioned during continuous therapy. Two patients had drug tolerance were required to increase the dose. CONCLUSION: Intrathecal baclofen is a good treatment for spasticity, it can be considered safe as it caused no serious side effects, intrathecal baclofen is safer than oral baclofen because is uses a smaller dose, and it regarding tolerance, it occurs but not in every patient.  

DOI

10.52573/ipmj.2020.169711

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