Abstract
ABSTRACT: BACKGROUND: Host genetic factors such as human leukocyte antigens (HLA) and non-HLA genes that are associated with the susceptibility to tuberculosis (TB) will serve as genetic markers to predispose or predetermine the development of the disease. OBJECTIVE: The aim of this study is to analyze the association between particular HLA-typing class I and the incidence of pulmonary tuberculosis in Baghdad city. PATIENTS & METHODS: Blood samples were collected from one hundred patients; 50 samples from patients with pulmonary tuberculosis referred to the Chest and Respiratory Diseases Institute in Baghdad city and 50 samples from apparently healthy individuals. All samples were submitted to the lymphocytotoxicity test (NIH) and examined in Major Histocompatibility Laboratory in AL- Karama Hospital in Baghdad city. RESULT: It was found that HLA (15) expression was significantly higher in recently infected patients with tuberculosis than in the controls (p
Recommended Citation
Manhal, Falah Salim
(2009)
"Allelic Distribution of Human Leukocyte Antigen in Patients with Pulmonary Tuberculosis in Baghdad City,"
Iraqi Postgraduate Medical Journal: Vol. 8:
Iss.
3, Article 10.
Available at:
https://www.ipmj.org/journal/vol8/iss3/10