Abstract
ABSTRACT: BACKGROUND: Hepatitis B virus (HBV) infection is a major public health problem. Successful clearance of the virus depends on a complex interaction between the virus and the host immune response. OBJECTIVE: This study was designed to estimation granulocyte macrophage-colony stimulating factor (GM-CSF) in HBV infected patients and individuals vaccinated with recombinant HB vaccine. METHODS: Study groups were classified into patient group 31(15 acute (AH) and 16 chronic (CH)), 33 vaccinated group (20 responder (RD) and 13 Non-responder (NRD)) and 16 healthy control (HC) during May to November 2007. Blood samples were taken from patients and hospitals staffs to detection hepatitis B surface antigen(HBsAg), anti-hepatitis B core antibody(IgM)(Anti-HBc Ab(IgM), anti hepatitis B surface antibody) (Anti-HBs Ab), GM-CSF level in serum by enzyme linked immunosorbent assay (ELISA) test. RESULTS: A highly significant elevation (p0.05) according to LSD- test. The level of GM-CSF also significantly higher (p
Recommended Citation
Ahmed, Hiwa Abdul -Rahman and Al-Barzinji, Rukia Muhammad.
(2010)
"Estimation of GM-CSF in Hepatitis B Virus Infected Patients and Individuals Vaccinated With Recombinant HB Vaccine,"
Iraqi Postgraduate Medical Journal: Vol. 9:
Iss.
2, Article 18.
Available at:
https://www.ipmj.org/journal/vol9/iss2/18