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Abstract

ABSTRACT: BACKGROUND: Hepatitis B virus (HBV) infection is a major public health problem. Successful clearance of the virus depends on a complex interaction between the virus and the host immune response. OBJECTIVE: The purpose of this study was to assessment of some immunoglobulins (IgG and IgM) in hepatitis patients and vaccinated groups compared with healthy control. METHODS: Study groups were classified into patient group 35 (15 acute (AC) and 20 chronic (CH)) and 35 vaccinated group (20 responder (RD) and 15 Non-responder (NRD)) and 18 healthy non vaccinated control group (HN). This study extended through a period from May to November 2007. Blood samples were taken from patients and hospitals staffs in Nanakaly, Erbil and Rizgary Teaching Hospital/ Erbil/ Iraq to detection of IgG and IgM level in serum by immunoturbidimetric test. RESULTS: The mean serum IgG level significantly increased in CH patients (p

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